Biomimetic and
Antibacterial Composite for Orthopedic Implants
Reka BALINT1,
Gertrud Alexandra PALTINEAN1, Diana Alexandra FLOREA1,2, Gheorghe TOMOAIA3,4, Aurora MOCANU1, Maria TOMOAIA-COTISEL1,4,*
1Babeş-Bolyai University, Faculty of Chemistry and
Chemical Engineering, Research Center
of Physical Chemistry, 11 Arany Janos Str., RO-400028, Cluj-Napoca,
Romania,
2Iuliu Haţieganu
University of Medicine and Pharmacy, Faculty of Dentistry, 8 Babeș V.
Str., Cluj-Napoca, RO-400012, Romania
3Iuliu Hatieganu
University of Medicine and Pharmacy, Department of Orthopedics and
Traumatology, 47 General Traian Mosoiu Street,
RO-400132 Cluj-Napoca, Romania
4Academy of Romanian Scientists, 3 Ilfov Street,
RO-050044, Bucharest, Romania
*Corresponding author: Maria
Tomoaia-Cotisel, mcotisel@gmail.com
Abstract. The present paper
shows how the development of synthetic nanostructured biomaterials, such as multisubstituted hydroxyapatite (msHAP)
with Mg2+, Zn2+ and Sr2+ ions is important and
beneficial at the same time for the normal functioning of the body. Moreover,
the paper discusses a broad topic of major importance in orthopedic
and dental surgery, namely the incorporation of msHAP
into the polymeric matrix of poly lactic acid (PLA). This composite is used in
order to cover the surface of the titanium implant in order to obtain bone
integration and heal bone fractures. The review also highlights the importance
of improving silver nanoparticle (SNPs) coating in order to combat
postoperative infections. Through such approaches, medicine has managed to
evolve considerably, and the contributions brought by great personalities and
young researchers in the field have increased its area of applicability.
Keywords:
multi-functional hydroxyapatites, orthopedic (medical) implants, silver
nanoparticles
DOI https://doi.org/10.56082/annalsarscibio.2022.1.120
